SpilianakisLab

Doxaki C, Kampranis SC, Eliopoulos AG, Spilianakis C, Tsatsanis C. Coordinated Regulation of miR-155 and miR-146a Genes during Induction of Endotoxin Tolerance in Macrophages. J Immunol. 2015, 195: 5750-5761

Stratigi K., Kapsetaki M., Aivaliotis M., Town T., Flavell RA., Spilianakis CG. Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression. Proc Natl Acad Sci U S A., 2015, 112:E1577-1586

Zorca CE, Kim LK, Kim YJ, Krause MR, Zenklusen D, Spilianakis CG, Flavell RA. Myosin VI regulates gene pairing and transcriptional pause release in T cells. Proc Natl Acad Sci U S A., 2015, 112:E1587-1593

Williams A., Lee G.R., Spilianakis C.G., Hwang S.S., Eisenbarth S.C., Flavell R.A. Hypersensitive site 6 of the Th2 locus control region is essential for Th2 cytokine expression. Proc Natl Acad Sci U S A., 2013, 110: 6955-6960

Deligianni C, Spilianakis C. Long-range genomic interactions epigenetically regulate the expression of a cytokine receptor. EMBO Reports, 2012, 13:819-826

Ktistaki E, Garefalaki A, Williams A, Andrews SR, Bell DM, Foster KE, Spilianakis CG, Flavell RA, Kosyakova N, Trifonov V, Liehr T, Kioussis D. CD8 locus nuclear dynamics during thymocyte development. J Immunol. 2010, 184(10):5686-95.

Williams A, Spilianakis CG, Flavell RA. Interchromosomal association and gene regulation in trans. Trends Genet. 2010, 26(4):188-97.

Deligianni C, Spilianakis C.G. Long range genomic cytokine-receptor interaction regulates gene expression. Cytokine 2009;48: 1-2, Sp. Iss. SI Pages: 2-2.

Spilianakis C.G. Interchromosomal cytokine gene regulation. Cytokine 2009; 48: 1-2, Sp. Iss. SI   Pages: 3-3.

Amsen D, Spilianakis CG, Flavell RA. How are T(H)1 and T(H)2 effector cells made? Curr. Opin.Immunol. 2009, 2: 153-60.

Brown MR, Kronengold J, Gazula VR, Spilianakis CG, Flavell RA, von Hehn CA, Bhattacharjee A, Kaczmarek LK. Amino-termini isoforms of the Slack K+ channel, regulated by alternative promoters, differentially modulate rhythmic firing and adaptation. J Physiol. 2008 , 586(Pt 21):5161-79.

Town T, Breunig JJ, Sarkisian MR, Spilianakis CG, Ayoub AE, Liu X, Ferrandino AF, Gallagher AR, Li MO, Rakic P, Flavell RA. The stumpy gene is required for mammalian ciliogenesis. Proc Natl Acad Sci U S A. 2008, 105(8):2853-8.

Spilianakis C.G., Flavell R.A. Epigenetic regulation of Ifng expression. Nat Immunol. 2007, 8:681-3.

Spilianakis C.G., Flavell R.A. Molecular biology. Managing associations between different chromosomes. Science 2006, 312:207-8.

Lee G.R., Kim S.T., Spilianakis C.G., Fields P.E., Flavell R.A. T helper cell differentiation: Regulation by cis-elements and epigenetics. Immunity 2006,4:369-79.

Gialitakis M., Kretsovali A., Spilianakis C.G., Kravariti, L., Mages J., Hoffmann R., Hatzopoulos A.K., Papamatheakis J. Coordinated changes of histone modifications and HDAC mobilization regulate the induction of MHC class II genes by Trichostatin A. Nucleic Acids Res. 2006, 34:765-72.

Spilianakis C.G., Lee G.R., Flavell R.A. Twisting the Th1/Th2 immune response via the retinoid X receptor: Lessons from a genetic approach. Eur J Immunol. 2005, 35:3400-4.

Spilianakis C.G., Lalioti M., Town T., et al. Epigenetic regulation of cytokine gene expression. Immunology 2006, 116: 30-30   Supplement: Suppl.1

Spilianakis C.G., Lalioti M., Town T., Lee GR., Flavell RA. Interchromosomal associations between alternatively expressed loci. Nature (Research Article). 2005, 435:637-645.

Lee GR, Spilianakis C.G., Flavell RA. Hypersensitive site 7 of the TH2 locus control region is essential for expressing TH2 cytokine genes and for long-range intrachromosomal interactions. Nat Immunol. 2005, 6:42-8.

Spilianakis C.G., Flavell RA. Long-range intrachromosomal interactions in the T helper type 2 cytokine locus. Nat Immunol. 2004, 5:1017-27.

Muhlethaler-Mottet A., Krawczyk M., Masternak K., Spilianakis C.G., Kretsovali A., Papamatheakis J., Reith W. The S box of major histocompatibility complex class II promoters is a key determinant for recruitment of the transcriptional co-activator CIITA. J Biol Chem. 2004, 279:40529-35.

Spilianakis C.G., Kretsovali A., Agalioti T., Makatounakis T., Thanos D., Papamatheakis J. CIITA regulates transcription onset viaSer5-phosphorylation of RNA Pol II. EMBO J. 2003, 22:5125-36.

Tzortzakaki E., Spilianakis C.G., Zika E., Kretsovali A., Papamatheakis J. Steroid receptor coactivator 1 links the steroid and interferon gamma response pathways. Mol Endocrinol. 2003, 12:2509-18.

Spilianakis C.G., Kretsovali A., Dimakopoulos A., Makatounakis T., Papamatheakis J. Self-association of class II transactivator correlates with its intracellular localization and transactivation. J Biol Chem. 2001, 276:32191-7.

Spilianakis C.G., Papamatheakis J, Kretsovali A. Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes. Mol Cell Biol. 2000, 20:8489-98.

Kretsovali A., Agalioti T., Spilianakis C.G., Tzortzakaki E., Merika M., Papamatheakis J. Involvement of CREB binding protein in expression of major histocompatibility complex class II genes via interaction with the class II transactivator. Mol Cell Biol. 1998, 18:6777-83.